Studies have shown that ketone supplement formulation may be a novel therapeutic for protecting and improving brain health in obese patients in 2023. People with obesity are known to be at a higher risk of cognitive impairment and neurodegenerative diseases.

A new study identified that giving obese patients a ketone supplement three times daily for fourteen days enhanced blood flow to the brain, improving aspects of cognitive function, including working memory and processing speeds. The ketone supplement formulation used includes BHB which is safe for human consumption and relatively new. It has shown that ketone supplements are beneficial for older adults with mild cognitive impairments and dementia, now this study focused on the same for obese patients.

The study focused on findings by demonstrating that ketone supplements can be novel therapeutic strategies to protect and improve brain health in obese people, focusing on those at risk of neurocognitive impairments. Adults with obesity volunteered to consume a ketone supplement formula or a taste-matched placebo, three times daily. The supplement was taken fifteen minutes before each meal, three times a day.

The study, a randomized placebo-controlled crossover study, provided volunteers with ketone supplements or a placebo for fourteen days, then they switched them for another fourteen days. This enables the researchers to compare the responses to the supplement and placebo in the same volunteers. All meals and snacks were provided for fourteen days.

Terry Kitagawa, the Nutrition Product Development Manager at Avila, a leading ketone supplement formulation specialist, said “The study measured the cognitive function using validated tests, measuring brain blood flow. They took blood samples to measure hormones that fuel the brain, especially those that improve cognitive functions and neuron growth. The conclusion is that ketone supplements could be used to protect and improve brain health in obese adults.”

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