of exogenous testosterone or its precursor. In addition, the supplementation of ElJ at this dosage and duration was safe because it did adversely have an effect on the liver and renal functions.

Seven compounds were isolated from the roots of Eurycoma longifolia, and characterized by comprehensive analysis of 1D and 2D NMR experiments along with single crystal X-ray diffraction. Among them, four new quassinoids were identified and 3 of them were diastereomers for each other. Compounds one-seven were evaluated for cytotoxicities against HT-29, MCF-seven, LOVO, BGC-823, MGC-803, HepG2, HeLa, and A549 cancer cell lines. Compounds two and 5 exhibited very cheap IC50 values of twenty four.nine µM, 11.eight µM, and forty four.1 µM, fourteen.one µM towards MCF-7, MGC-803 cancer cell lines, respectively, while compound half-dozen exhibited moderate cytotoxicity towards all the chosen cancer cell lines.
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