O/P-Toluenesulfonamide (CAS NO. 1333-07-9): Properties, Synthesis, and Applications


Posted October 22, 2024 by jiaxingjinli

O/P-toluenesulfonamide (CAS NO. 1333-07-9) is a versatile compound widely used in organic synthesis and various industrial applications.
 
O/P-toluenesulfonamide (CAS NO. 1333-07-9) is a versatile compound widely used in organic synthesis and various industrial applications.

Introduction to O/P-Toluenesulfonamide (CAS NO. 1333-07-9)
O/P-toluenesulfonamide (CAS NO. 1333-07-9) is an aromatic sulfonamide characterized by the presence of a toluene sulfonamide group. This compound exists in both ortho (O) and para (P) configurations, influencing its chemical behavior and applications.

Chemical Properties of O/P-Toluenesulfonamide (CAS NO. 1333-07-9)
Molecular Structure
The molecular formula for O/P-toluenesulfonamide (CAS NO. 1333-07-9) is C7H9NO2S. The sulfonamide functional group contributes to its reactivity, making it suitable for various chemical transformations.

Physical Characteristics
O/P-toluenesulfonamide (CAS NO. 1333-07-9) typically appears as a white to light yellow crystalline solid. It is soluble in polar solvents like water and ethanol, facilitating its use in numerous chemical reactions and formulations.

Synthesis of O/P-Toluenesulfonamide (CAS NO. 1333-07-9)
Common Synthetic Methods
Reaction with Toluene Sulfonyl Chloride: A common method for synthesizing O/P-toluenesulfonamide (CAS NO. 1333-07-9) involves the reaction of toluene sulfonyl chloride with ammonia or an amine. This reaction typically yields high-purity product in good yields.

Alternative Approaches: Another method may include the sulfonation of aniline followed by careful separation of the ortho and para isomers to obtain the desired compound.

Applications of O/P-Toluenesulfonamide (CAS NO. 1333-07-9)
In Organic Synthesis
O/P-toluenesulfonamide (CAS NO. 1333-07-9) is a crucial reagent in organic synthesis. It is commonly used to produce various pharmaceutical intermediates, including sulfonamide drugs, which possess antibacterial properties.

In Agriculture
This compound finds applications in agricultural chemistry as well. O/P-toluenesulfonamide (CAS NO. 1333-07-9) is used in the development of herbicides and pesticides, contributing to improved crop protection and yield.

In Dye and Pigment Production
O/P-toluenesulfonamide (CAS NO. 1333-07-9) is also utilized in the dye and pigment industry. Its ability to act as a coupling agent in dye synthesis makes it valuable in producing vibrant and stable colors.

Safety Considerations for Handling O/P-Toluenesulfonamide (CAS NO. 1333-07-9)
Toxicity Information
When working with O/P-toluenesulfonamide (CAS NO. 1333-07-9), it is essential to understand potential health risks. Always refer to safety data sheets (SDS) for comprehensive toxicity information. Proper personal protective equipment (PPE) such as gloves and goggles should be worn to minimize exposure.

Environmental Impact
Care should be taken to prevent the release of O/P-toluenesulfonamide (CAS NO. 1333-07-9) into the environment. Proper disposal methods in accordance with local regulations are essential to ensure safe handling and reduce ecological risks.

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Last Updated October 22, 2024