Bone Glue Market, by Product Type (Synthetic Bone Glue and Natural Bone Glue), by Therapeutic Application (Osteoporosis, Sports Injuries, Spinal Injuries, Traumatic Bone Fracture, and Bone Tumor), by End User (Hospitals, Clinics, Specialized Orthopedic Clinics, and Ambulatory Surgical Centers), and by Region (North America, Latin America, Europe, Asia Pacific, Middle East, and Africa) - Size, Share, Outlook, and Opportunity Analysis, 2019-2027

Bone Glue Market Insights
Osteoporosis is common cause for bone fractures and its prevalence gradually increases with age. For instance, according to the National Center for Biotechnology Information, the prevalence of osteoporosis is 10% in men and 13% in women, who are aged 60 years or above. Moreover, according to the National Osteoporosis Foundation data, 2014, around 54 million U.S. adults aged 50 and above were affected by osteoporosis and low bone mass in 2013. It further states that the number of bone fractures will increase by 2 to 4 times by 2020 and 41 million women will suffer from osteoporosis or osteoarthritis. This is mainly attributed to significant rise in geriatric population.

Bone health significantly deteriorates with age, which leads to large number of accidents and resultant fractures. For instance, according to the National Osteoporosis Foundation in 2014, around 10.2 million adults had osteoporosis and another 43.4 million had low bone mass, which accounted over one-half of the total U.S. adult population were affected by bone disorders in 2013. This is expected to boost growth of the bone glue market. According to Medanta Medicity, a major multi-specialty hospital based in India, Indians have 15% lower bone density, which showcases Indians at a greater risk of broken bones compared to Caucasians.

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The global bone glue market size is estimated to be valued at US$ 1,981.77 million in 2019 and is expected to exhibit a CAGR of 5.7% over the forecast period (2019-2027).

Increasing number of bone disorders and rising number of arthroplasty are expected to drive growth of the global bone glue market

Increasing prevalence of bone disorders and rising geriatric population are major factors that are expected to drive growth of the bone glue market. For instance, according to the report of Arthritis Foundation of 2018, osteoarthritis (OA) is the most common bone and joint disorder in the U.S., wherein around 30.8 million U.S. adults suffer from osteoarthritis. Furthermore, according to the same source, osteoarthritis is the most common cause of disability in the U.S. adults aged 60 and above.

Increasing number of arthroplasty procedures and rising demand for newer bone glues across various economies in North America and Europe are expected to fuel growth of the bone glue market over the forecast period. For instance, according to the Journal of Bone and Joint Surgery published data in September 2018, total hip arthroplasty (THA) is expected to exhibit a CAGR of 71% to reach 635,000 procedures by 2030 and primary total knee arthroplasty (TKA) is expected to grow by 85% to reach 1.26 million procedures by 2030.

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Global Bone Glue Market- Restraints
However, stringent regulations in the U.S. such as institutions and universities that use animals for research purpose should be licensed and or registered with the U.S. Department of Agriculture. Moreover, facilities and regulated animals must be inspected yearly by the USDA’s Animal and Plant Health Inspection Service and these factors are expected to hamper the market growth due to inhibition in the production of natural glue obtained from animals.

Non-animal substitutes such as synthetic glue is relatively more expensive and can also lead to compatibility issues with bones. Difficulties such as irritation caused by the cement to the surrounding skin over prolong application, breakdown of the cement causes artificial joint to come loose, and breakage of cement in bits that are associated with cemented arthroplasty are main concerns, which is expected to hamper growth of the bone glue market over the forecast period.

Global Bone Glue Market- Regional Insights
On the basis of region, the global bone glue market is segmented into North America, Latin America, Europe, Asia Pacific, Middle East, and Africa. North America is expected to hold dominant position in the global bone glue market, owing to increasing initiatives by key players in this region. Advancements in technologies by key players is expected to drive the market growth. For instance, in 2015, LaunchPad Medical, LLC entered into a definitive agreement to receive license from Stryker Corporation's for a novel bone adhesive technology. This technology is based on unique synthetic biomaterial.

Europe is expected to be the fastest growing region in the global bone glue market, owing to increasing research and development activities about bone glue products. For instance, in April 2018, researchers from the KTH Royal Institute of Technology in Stockholm, Sweden developed an adhesive glue that is used the basic bonding technique with thiol-ene coupling (TEC) technology, which hardens and sets reliably even when exposed to water and oxygen. The adhesive technique is three-layered, much like a sandwich of biocompatible glue and fiber. This effective glue could provide an optimal solution for acute bone fractures and sudden painful damage to the bone.

Global Bone Glue Market- Competitive Landscape
Key players operating in the global bone glue market include Cryolife, Luna Innovations Incorporated., Johnson and Johnson, Cohera Medical Inc, Tissuemed Ltd., Integra Lifesciences Corporation, Baxter International Inc., B.Braun Melsungen AG, DENTSPLY SIRONA Inc., Chemence Medical Inc., LaunchPad Medical, and C.R. Bard Inc.

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