Ephedrine Market, By Dosage Form (Tablets, Capsules, and Injections), By Disease Indication (Bronchial Asthma, Spinal Anesthesia induced Hypotension, and Others), By Distribution Channel (Hospital Pharmacies, Retail Pharmacies, and Others), and By Region (North America, Latin America, Europe, Asia Pacific, Middle East, and Africa) - Size, Share, Outlook, and Opportunity Analysis, 2019 – 2027
Ephedrine is a decongestant and bronchodilator, used to treat bronchospasms caused due to asthma. The medicine reduces the swelling and constricts the blood vessels in the nasal passages which widens the lung airways and allows the patient to breathe easily. Due to the medicine’s central nervous system stimulatory effects, ephedrine is also used extensively during spinal anesthesia in order to prevent intra-operative hypotension. The medicine is available in the form of tablets, capsules and injections.
Global Ephedrine Market – Dynamics
High prevalence of hypotension during spinal anesthesia is expected to propel growth of the ephedrine market over the forecast period. For instance, according to the Columbian Journal of Anesthesiology, 2018, incidences of hypotension during spinal anesthesia ranges from 1.9% to 71% globally.
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Moreover, launches and approvals of ephedrine products is expected to boost the ephedrine market growth over the forecast period. For instance, in January 2017, Par Pharmaceutical, a subsidiary of Endo International plc, received approval from the U.S. Food and Drug Administration (FDA) for its new ephedrine sulfate injection, CORPHEDRA. The injection will be used to for the treatment of hypotension occurring in the process of spinal anesthesia.
However, restrictions on ephedrine usage through regulatory authorities is expected to restrain the market over the forecast period. For instance, since 2001, the Government of Canada has authorized ephedrine only as a nasal decongestant with a maximum dosage of 8mg along with 32mg in a 24 hour period.
Global Ephedrine Market – Regional Insights
North America accounted for the largest market share in 2018, owing to launches and approvals of new ephedrine products in the region. For instance, in March 2017, Akorn, Inc., a developer and manufacturer of generics and branded prescription pharmaceuticals, received the U.S. Food and Drug Administration (FDA) approval for its New Drug Application (NDA) for single dose ampule of an ephedrine sulfate injection which is indicated for treating hypotension occurring during spinal anesthesia.
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Increasing ephedrine product launches is expected to propel the market growth in the Europe region. For instance, in April 2016, Avadel Pharmaceuticals, formerly known as Flamel Technologies, received approval from the U.S. Food and Drug Administration for Akovaz, an ephedrine sulfate injection, which will be used to treat hypotension occurring during anesthesia.
Moreover, high prevalence of hypotension during spinal anesthesia in Asia Pacific is likely to drive the ephedrine market over the forecast period. For instance, according to a study published in the Indian Journal of Anesthesia, 2018, the cases of mild, moderate, and severe spinal anesthesia induced hypotension was approximately 20%, 35%, and 40% respectively.
Global Ephedrine Market – Competitive Landscape
Key player operating in the market include Servier, Merck Sharp & Dohme Corp., Amgen Inc., Sanofi S.A., Avadel Pharmaceuticals, GlaxoSmithKline plc, Endo Pharmaceuticals plc, and Akorn Inc.
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