Granulators for Pharmaceutical Market, by Product Type (Single Pot Granulators, High Sheer Granulators, Fluid Bed Granulators, Rapid Mixer Granulators, Oscillating Granulators, and Others), by Application (End Product Manufacturing, Solid Dosage Formulation, API Manufacturing, and Others), by Granulation Mechanism (Dry Granulators, Wet Granulators, and Mixed Granulators), by End User (Pharmaceutical Manufacturing Companies, Contract Manufacturing Organizations, Research Institutes, and Others), and by Region - Global Forecast to 2025
Granulators for Pharmaceutical Market – The Story of Pill Formation
Granulators are rotor machines that converts fine powder to granules through a series of physical process. Granulation is a process, where small particles are gathered together to form a large permanent mass, in which original particles can still be identified. Granulation has applications in pharmaceutical drug manufacturing for manufacturing tablets, capsules, and other forms of drugs. The granulated material is achieved by size enlargement of primary particles or size reduction from dry compacted material. The multi-particle entities that are formed as a result of granulation creates bond between the particles through compression with the help of a binding agent. Granulation is one of the most important unit operations involved in the production of pharmaceutical oral dosage forms. Furthermore, granulation is carried out with the help of granulators that are available in different technologies. The pharmaceutical drug manufacturing companies choose one of these granulators based on the demand from the drug and its formulation. They help to deliver correct form of dosage and maintain the chemical integrity of pharmaceutical product. Expansion of pharmaceutical manufacturing units and new pharmaceutical players entering in the market are the primary factors that are expected to drive growth of the granulators for pharmaceutical market. For instance, in 2013, the Supreme Council of Health Pharmacy and Drug Control Department of Qatar announced three new domestic drug manufacturers to cut down on drug importing and start production within the economy for a number of drugs and vaccines.
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The global granulators for pharmaceutical market was valued at US$ 5,486.44 million in 2016 and is expected to exhibit a CAGR of 5.40% over the forecast period (2017-2025).
Several initiatives taken by government and non-government organization to scale up pharmaceutical manufacturing process leading to number of new and existing players entering the production sector are the major factors that are expected to drive the market growth. The entry of local players in the pharmaceutical industry is accompanied by funding and subsidies provided to these players in terms of facility & equipment set-up helps the companies to start small and mid-sized manufacturing units. Granulators are an integral part of these units, as these are the primary stage unit processors in oral dosage formulations. For instance, according to the provisions of 2015-16 Union Budget of India, a national center to develop bulk drugs and facilitate their research was set up in Hyderabad. Automation of drug development procedure involves installation of upgraded automatic instruments, which is propelling demand for pharmaceutical granulators. For instance, in July 2017 Boehringer Ingelheim invested US$ 217 Million to upgrade and expand its manufacturing facility in Fremont, California. Furthermore, in 2012 the new release for GMP upgrade of a production facility for solid pharmaceuticals includes procurement of new production equipment such as granulator and dryer, capsule deduster, and others.
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Among regions, North America is expected to hold dominant position in the global granulators for pharmaceutical market, owing to presence of leading pharmaceutical manufacturers in the region with huge production plants that involve mass manufacturing and development of oral pharmaceutical drugs. Moreover, production facility expansion by existing pharmaceutical players and startup of new production plant by emerging market players in the pharmaceutical industry are further expected to drive growth of North America market. For instance, in September 2017, Fresenius Kabi announced about an investment of US$ 250 million to establish a pharmaceutical plant in Illinois, U.S. for aseptic manufacturing of pharmaceutical drugs in the company’s portfolio. In March 2017, Apotex, Inc. a Canada-based pharmaceutical company announced an investment of US$ 184 million for expansion of advanced manufacturing and R&D facility in Florida, U.S. Moreover, Asia Pacific is expected to witness a significant traction in the granulators market over the forecast period, owing to major investments by global and regional pharmaceutical players for expansion of the production units. For instance, in March 2018, Merck KGaA invested US$ 47 million for expansion of manufacturing plants in South Korea and India to develop biologics and other pharmaceutical drugs. Furthermore, emerging economies in Asia Pacific such as India has a considerable manufacturing expertise and holds a significant position in production of various number of generic drugs and vaccines. For instance, according to the Indian Brand Equity Foundation (IBEF) 2017, India accounted for around 20% of global exports in generic drugs and has an immense potential for growth.
However, high cost associated with these systems, which make them unaffordable for small emerging players due to limited investment capacity are expected to hinder the market growth over the forecast period.
Market players focused on development of innovative products to maintain leading position in global granulators for pharmaceutical market
Key players are focused on developing novel, innovative, and smart products to maintain leading position in granulators market. For instance, in July 2017, Wittmann introduced a new G-Max 23 granulator, which is a flexible, custom-made granulator that consumes less energy and delivers high performance. Moreover, in 2015, Bosch GmBH developed a new granulation unit Granulean, a novel pharmaceutical granulator that collectively carries out the process of mixing, granulating, and drying of the pharmaceutical granules.
Key players operating in the global granulators for pharmaceutical market include Bosch Packaging Technology, Alexanderwerk, GEA Pharma Systems, Frewitt Pharma Machinery, Diosna, Fluid Air, Inc., Romako Pharmatechnik GmbH, and Gebrüder Lödige Maschinenbau GmbH.
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