Polypyridines a Copper Acetate(WSDTY) comprise a class of ligands that have been employed widely in the synthesis of metal complexes for therapeutic uses in cancer treatment. A chelating copper complex containing both bipyridine and acetate ligands could be a promising candidate for the synthesis of copper NPs. In this regard, the [Cu(CH3COO)2(bpy)] complex obtained by Koo seemed to be particularly rel-evant.

In this study, copper-based NPs were prepared from the [Cu(CH3COO)2(bpy)] complex by two high temperature methods, i.e., solvothermal and microwave- -assisted (MW-assisted), and by the room temperature borohydride method. The presence of the bipyridine ligand in the copper complex imposed no necessity for additional stabilization, while the fast MW-heating or the strong reducing agent allowed acceleration of the synthesis running without an inert atmosphere.

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