E. coli and the bacteria group Proteus, Staphylococcus, Enterococcus, Pseudomonas aeruginosa, Klebsiella, and mycoplasma, fungi and viruses. Contributing factors for the occurrence of the disease may include: urolithiasis disease; congenital or acquired stricture (narrowing) of the ureter; nephroptosis (kidney ptosis); anomalies of the supplement manager kidney and ureter; the presence of chronic infection (dental caries, tonsillitis, mastitis, pulp). Clinical manifestations of chronic pyelonephritis are varied and depend largely on the phase of the disease. There are 3 phases of the disease: the phase of active inflammation; phase of latent (hidden) inflammation; phase response (clinical cure). During active inflammation appear severe pain in the back, from the side of the abdomen, accompanied by fever, chills, often joined by nausea and vomiting. Urination can be speeded up or rare in this period. The amount of urine may decrease or remain normal. Urine becomes turbid, sometimes with an admixture of flakes and / or colored blood. Also, the phase of active inflammation accompanied by severe weakness, fatigue, decreased ability to work, and lack of appetite. The blood and urine analysis revealed a large number of leukocytes (inflammatory .

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