MRRS adds "Global Urological Cancer Market to 2022 – Strong Growth Driven by Rising Prevalence, Increased Uptake of Hormone Therapies and Approval of Novel Biologics" latest studies, published in November 2016. It is a professional and in-depth study.

Summary
Urological cancers are thought to account for 19.5% of global cancer prevalence, with kidney, prostate, testicular and bladder cancer – the key indications covered in this report – accounting for the majority of that figure. Urological cancers affect the male and female urinary tract and the male reproductive organs. Prostate cancer is the most prevalent of these malignancies.

A number of common etiologic factors have been strongly characterized as raising the risk of developing urological cancers, including age, chronic inflammation, gender, obesity, tobacco usage and heritable cancer syndromes. The risk of cancer increases greatly in patients over the age of 65. Populations in developed countries are projected to become increasingly aged and show rising obesity incidence, which will drive both cancer prevalence and revenue growth for its treatments.

Hormone therapies for prostate cancers and angiogenesis inhibitors for renal cell carcinoma are currently the most commercially successful urological cancer drugs. However, there has been a shift towards the clinical testing of cancer immunotherapies – such as Opdivo, which was recently approved for renal cell carcinoma. The forecast period will also witness the approval of a greater number of targeted therapies, which by their nature have less toxicity associated with their use, and as a result can be administered to patients with poor performance statuses, therefore increasing the overall survival of this group and the number of treatment cycles they may receive.

Table of Contents
3 Key Marketed Products 23
3.1 Overview 23
3.2 Zytiga (abiraterone acetate) 23
3.3 Xtandi (enzalutamide) 25
3.4 Sutent (sunitinib malate) 26
3.5 Votrient (pazopanib hydrochloride) 27
3.6 Inlyta (axitinib) 28
3.7 Jevtana (cabazitaxel) 29
3.8 Xofigo (radium Ra 223 dichloride) 31
3.9 Provenge (sipuleucel-T) 32
3.10 Opdivo (nivolumab) – Bristol-Myers Squibb 33
3.11 Conclusion 34
4 Pipeline Landscape Assessment 35
4.1 Overview 35
4.2 Pipeline Development Landscape 36
4.3 Molecular Targets in the Pipeline 39
4.4 Clinical Trials 43
4.4.1 Failure Rate by Stage of Development, Indication, Molecule Type and Molecular Target 44
4.4.2 Clinical Trial Duration by Stage of Development, Indication, Molecule Type and Molecular Target 48
4.4.3 Clinical Trial Size by Stage of Development, Indication, Molecule Type and Molecular Target 52
4.4.4 Aggregate Clinical Program Size by Stage of Development, Indication, Molecule Type and Molecular Target 56
4.5 Conclusion 60
4.6 Assessment of Key Pipeline Products 61
4.6.1 Atezolizumab – Roche 61
4.6.2 Durvalumab – AstraZeneca 62
4.6.3 Durvalumab + Tremelimumab – MedImmune 63
4.6.4 Apalutamide – Johnson & Johnson 64
4.6.5 Avelumab – Merck KGaA 65
4.6.6 Tivozanib – EUSA Pharma 66
4.6.7 Eoquin – Spectrum Pharmaceuticals 67
4.6.8 Prostvac – Bavarian Nordic 68
4.7 Conclusion 69
5 Multi-Scenario Market Forecast to 2022 70......

List of Tables and Figures 
Table 1: Urologic Oncology, Global, Symptoms of the Most Prevalent Urological Cancers, 2016 10
Table 2: Urologic Oncology, Global, Complications Associated with Bladder, Kidney, Prostate and Testicular Cancers 13
Table 3: Urologic Oncology, Global, Epidemiology of The Most Prevalent Urological Cancers, 2015 14
Table 4: Urologic Oncology, Optimal and Actual Chemotherapy Usage Rates Across All Cancer Stages, 2010 19
Table 5: Urologic Oncology, Global, Reconstructive Surgery following Bladder Cancer Resection, 2016 20
Table 6: Urologic Oncology, Optimal and Actual Radiation Therapy Usage Rates in US, 1995–2000 21
Table 7: Urologic Oncology Therapeutics Market, Global, Approved Indications for Zytiga, 2016 24
Table 8: Urologic Oncology Therapeutics Market, Global, Approved Indications for Xtandi, 2016 25
Table 9: Urologic Oncology Therapeutics Market, Global, Approved Indications for Sutent, 2016 27
Table 10: Urologic Oncology Therapeutics Market, Global, Approved Indications for Votrient, 2016 28
Table 11: Urologic Oncology Therapeutics Market, Global, Approved Indications for Inlyta, 2016 29
Table 12: Urologic Oncology Therapeutics Market, Global, Approved Indications for Jevtana, 2016 30
Table 13: Urologic Oncology Therapeutics Market, Global, Approved Indications for Xofigo, 2016 31
Table 14: Urologic Oncology Therapeutics Market, Global, Approved Indications for Provenge, 2016 Table 15: Urologic Oncology Therapeutics Market, Global, Approved Indications for Opdivo, 2016 .....

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